Proteins are ubiquitous, large, complex and the most abundant macromolecule which play critical role in the normal functioning of living organisms. They are the product of DNA translation and are made up of amino acids linked to each other by a peptide bond. They can be described as “biological labourers” since they are essential for the structure, function, and regulation of the cells and tissues of the body. The function of a protein depends on correct folding (the three-dimensional structure) such that improper folding of a protein resulting from changes in its amino acid sequence leads to dysfunction and consequently manifesting as a disease or disorder. Thus, protein chemistry is central to biochemistry and spans the various branches of other subjects such as immunology, biophysics, enzymology, endocrinology etc. This course is therefore designed to equip students with the fundamentals of protein chemistry. The topics to be discussed include protein structure, protein-ligand interactions, chemical bonds/reactions involved in protein/protein and protein ligand interactions and mechanisms of enzyme action.
- Lecturer: Dr. Adjoa Boakye
- Lecturer: Mr. Rupert Delimini